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Computational simulation of JAK/STAT signaling in somatic versus germline stem cells.

Willis X Li
Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2023)
The simulation suggests that the duration of ligand exposure could explain the observed opposite effects of JAK/STAT activation on heterochromatin in somatic versus GSCs.
Keyphrases
  • stem cells
  • copy number
  • virtual reality
  • oxidative stress
  • dna methylation
  • dna damage
  • mesenchymal stem cells
  • bone marrow