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A Closed Chemobrionic System as a Biochemical Delivery Platform.

Georgios AngelisDimitris Nabil ZayedAnastasia KariotiDiamanto LazariEirini KanataTheodoros SklaviadisGeorgios Pampalakis
Published in: Chemistry (Weinheim an der Bergstrasse, Germany) (2019)
Inorganic cells bearing calcium silicate membranes were prepared and resembled closed chemical gardens. It was demonstrated that these inorganic cells can successfully be loaded with natural products, proteins and plasmid DNA, and their cargo can be released in a controlled manner. These cells demonstrated the ability of chemical gardens to act as platforms for the sustained delivery of biomolecules and are expected to introduce chemical gardens in the field of biosciences.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • escherichia coli
  • endoplasmic reticulum stress
  • cell death
  • oxidative stress
  • drug delivery
  • cell proliferation