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Movement and storage of nematocysts across development in the nudibranch Berghia stephanieae (Valdés, 2005).

Jessica A GoodheartVanessa BaroneDeirdre C Lyons
Published in: Frontiers in zoology (2022)
Our work highlights the utility of B. stephanieae for future research, because: (1) this species can be cultured in the laboratory, which provides access to all developmental stages, and (2) the transparency of early juveniles makes imaging techniques (and therefore cell and molecular assays) feasible. Our results pave the way for future studies using live imaging and targeted gene editing to identify the molecular mechanisms involved in nematocyst sequestration. Further studies of nematocyst sequestration in B. stephanieae will also allow us to investigate how common cellular mechanisms like phagocytosis can be modified to selectively internalize and store foreign structures.
Keyphrases
  • high resolution
  • current status
  • case control
  • single cell
  • cancer therapy
  • endothelial cells
  • stem cells
  • mass spectrometry
  • photodynamic therapy