Evaluation of [13N]ammonia positron emission tomography as a potential method for quantifying glutamine synthetase activity in the human brain.

Alice EgertonJoel T DunnNisha SinghZilin YuJim O'DohertyIvan KoychevJessica WebbSimon ClaridgeFederico E TurkheimerPaul K MarsdenAlexander HammersAntony Gee

Published in: EJNMMI research (2020)

The [13N]ammonia PET method was unable to reliably estimate GS activity in the human brain but may provide an alternative index of CBF.

Keyphrases

positron emission tomography
computed tomography
pet ct
pet imaging
anaerobic digestion
room temperature
human health