Role of HLA-DQ typing and antitissue transglutaminase antibody titres in diagnosing coeliac disease among Sudanese children with type 1 diabetes mellitus.
Ibtihag IbaidMohammed O HussienKatri KaukinenOmayma SabirMiskelyemen ElmekkiAzza B MusaNasreldein AbdelhadiAbdel Rahim El HusseinPäivi SaavalainenPublished in: BMJ open gastroenterology (2022)
Anti-TG IgA titre of greater than 10 times upper limit of normal (≥10× ULN) can be useful for detecting CD in children with type 1 diabetes without duodenal biopsy. HLA testing in children with DM1 appears to provide little added benefit given the high prevalence (96%) of HLA DQ2/DQ8 in children with DM1.