AT1 and AT2 Receptor Knockout Changed Osteonectin and Bone Density in Mice in Periodontal Inflammation Experimental Model.

Maria Laura de Souza LimaCaroline Addison Carvalho Xavier de MedeirosGerlane Coelho Bernardo GuerraRobson Augusto Souza Dos SantosMichael BaderFlavia Q PirihRaimundo Fernandes de Araújo JúniorAlan B ChanLuis J CruzGerly Anne de Castro BritoRenata Ferreira de Carvalho LeitãoEricka Janine Dantas da SilveiraVinícius Barreto GarciaAgnes Andrade MartinsAurigena Antunes de Araújo

Published in: International journal of molecular sciences (2021)

AT1 receptor knockout changed bone density, the quality and number of bone trabeculae, decreased the number of osteoblast cells, and increased osteonectin in fibroblasts.

Keyphrases

bone mineral density
bone regeneration
soft tissue
bone loss
induced apoptosis
postmenopausal women
type diabetes
wild type
binding protein
metabolic syndrome
cell proliferation
quality improvement
endoplasmic reticulum stress
skeletal muscle
insulin resistance