Chitinase-3-like 1-protein in CSF: a novel biomarker for progression in patients with multiple sclerosis.

Foraysa TalaatSahar AbdelattyChristine Ragaie Ahmed Dahshan

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2023)

CHI3L1 can be considered as a biomarker of disease progression. CHI3L1 level increases in progressive MS more than RRMS. Also, high CSF level of CHI3L1 was associated with more disability including motor, cognitive, and radiological aspects.

Keyphrases

multiple sclerosis
mass spectrometry
ms ms
cerebrospinal fluid