Physiologic effects of alveolar recruitment and inspiratory pauses during moderately-high-frequency ventilation delivered by a conventional ventilator in a severe lung injury model.

Ricardo Luiz CordioliEduardo Leite Vieira CostaLuciano Cesar Pontes AzevedoSusimeire GomesMarcelo Britto Passos AmatoMarcelo Park

Published in: PloS one (2017)

During MHFPPV set with RR of 60 bpm delivered by a conventional ventilator in severe ARDS swine model, neither the inspiratory pauses or PEEP titration after recruitment maneuver allowed reduction of VT significantly, however the last strategy decreased driving pressures and improved both shunt and dead space.

Keyphrases

high frequency
mechanical ventilation
acute respiratory distress syndrome
transcranial magnetic stimulation
early onset
extracorporeal membrane oxygenation
intensive care unit
respiratory failure
pulmonary artery
pulmonary arterial hypertension
pulmonary hypertension