DNA methylation subclass receptor tyrosine kinase II (RTK II) is predictive for seizure development in glioblastoma patients.

Franz L RicklefsRichard DrexlerKathrin WollmannAlicia EckhardtDieter H HeilandThomas SauvignyCecile MaireKatrin LamszusManfred Westphal Ulrich SchüllerLasse Dührsen

Published in: Neuro-oncology (2022)

Our study shows a strong correlation of RTK II glioblastomas with preoperative and long-term seizures. These results underline the benefit of molecular glioblastoma profiling with important implications for postoperative seizure control.

Keyphrases

tyrosine kinase
dna methylation
end stage renal disease
patients undergoing
epidermal growth factor receptor
newly diagnosed
ejection fraction
chronic kidney disease
gene expression
temporal lobe epilepsy
single cell
single molecule
copy number