Upregulated miR-1258 regulates cell cycle and inhibits cell proliferation by directly targeting E2F8 in CRC.

Zhiyuan ZhangJie LiYuanjian HuangWen PengWenwei QianJiou GuQingyuan WangTao HuDongjian JiBing JiYue ZhangShijia WangYueming Sun

Published in: Cell proliferation (2018)

MiR-1258 may function as a suppressive factor by negatively controlling E2F8, thus, highlighting the potential role of miR-1258 as a therapeutic target for human CRC.

Keyphrases

cell proliferation
cell cycle
long non coding rna
pi k akt
long noncoding rna
endothelial cells
drug delivery
cancer therapy
risk assessment
induced pluripotent stem cells
human health