Solid-state NMR at natural isotopic abundance for the determination of conformational polymorphism - the case of designed β-turn peptides containing di-prolines.
Jayasubba Reddy YaravaRajesh SontiK KantharajuS RaghothamaKrishna Venkatachala RamanathanPublished in: Chemical communications (Cambridge, England) (2018)
The proton double quantum-carbon single quantum correlation experiment has been applied to designed peptides in the solid state in natural isotopic abundance. Analogous to nOe studies in solution, through-space double-quantum connectivities have been exploited to obtain the cis-trans conformational polymorphism of diproline residues occurring at β-turns in the peptides.
Keyphrases
- solid state
- molecular dynamics
- molecular dynamics simulations
- amino acid
- single molecule
- antibiotic resistance genes
- energy transfer
- cystic fibrosis
- fluorescent probe
- living cells
- magnetic resonance
- sensitive detection
- solid phase extraction
- biofilm formation
- staphylococcus aureus
- pseudomonas aeruginosa
- molecularly imprinted
- high resolution
- wastewater treatment
- quantum dots
- candida albicans