Aortic Stiffness and Pulsatile Pressures as Potential Mediators of Chronic Kidney Disease Induced Impaired Diastolic Function.
Hon-Chun HsuGrace TadeGavin R NortonFerande PetersChanel RobinsonNoluntu DlongoloGloria TeckieAngela J WoodiwissPatrick Hector DesseinPublished in: International journal of nephrology and renovascular disease (2022)
Aortic stiffness rather than pulsatile pressures mediates CKD-related impaired left ventricular active relaxation. By contrast, aortic pulsatile pressures (and not stiffness) contribute to CKD-related left ventricular filling pressures but do not fully account for the respective association.
Keyphrases
- left ventricular
- chronic kidney disease
- end stage renal disease
- hypertrophic cardiomyopathy
- acute myocardial infarction
- cardiac resynchronization therapy
- heart failure
- aortic stenosis
- left atrial
- mitral valve
- aortic valve
- magnetic resonance
- drug induced
- high glucose
- pulmonary artery
- diabetic rats
- aortic dissection
- peritoneal dialysis
- computed tomography
- single molecule
- magnetic resonance imaging
- ejection fraction
- oxidative stress
- contrast enhanced
- endothelial cells
- percutaneous coronary intervention
- climate change
- acute coronary syndrome