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Histological Findings of Mammary Gland Development and Risk of Breast Cancer in BRCA1 Mutant Mouse Models.

Hyelim KimWoo Kyung Moon
Published in: Journal of breast cancer (2021)
BRCA1 mutant mice exhibited early pubertal mammary gland development and delayed age-related mammary gland involution was associated with breast cancer. Our results may have clinical implications for predicting breast cancer risk and developing prevention strategies for BRCA1 mutation carriers.
Keyphrases
  • breast cancer risk
  • wild type
  • mouse model
  • type diabetes
  • high fat diet induced
  • metabolic syndrome
  • insulin resistance