Histological Findings of Mammary Gland Development and Risk of Breast Cancer in BRCA1 Mutant Mouse Models.

Published in: Journal of breast cancer (2021)

BRCA1 mutant mice exhibited early pubertal mammary gland development and delayed age-related mammary gland involution was associated with breast cancer. Our results may have clinical implications for predicting breast cancer risk and developing prevention strategies for BRCA1 mutation carriers.

Keyphrases

breast cancer risk
wild type
mouse model
type diabetes
high fat diet induced
metabolic syndrome
insulin resistance