Quantitative metagenomics reveals unique gut microbiome biomarkers in ankylosing spondylitis.

Chengping WenZhijun ZhengTiejuan ShaoLin LiuZhijun XieEmmanuelle Le ChatelierZhixing HeWendi ZhongYongsheng FanLinshuang ZhangHaichang LiChunyan WuChangfeng HuQian XuJia ZhouShunfeng CaiDawei WangYun HuangMaxime BrebanNan QinStanislav Dusko Ehrlich

Published in: Genome biology (2017)

Alterations of the gut microbiome are associated with development of ankylosing spondylitis. Our data suggest biomarkers identified in this study might participate in the pathogenesis or development process of ankylosing spondylitis, providing new leads for the development of new diagnostic tools and potential treatments.

Keyphrases

ankylosing spondylitis
disease activity
rheumatoid arthritis
systemic lupus erythematosus
high resolution
machine learning
big data
risk assessment
electronic health record
human health