Nicotine Impairs Smooth Muscle cAMP Signaling and Vascular Reactivity.

Navid SinghraoVictor A Flores-TamezYumna A MoustafaGopireddy R ReddyAbby E BurnsKent E PinkertonChao-Yin ChenManuel F Navedo Madeline Nieves-Cintron

Published in: Microcirculation (New York, N.Y. : 1994) (2024)

These results imply that nicotine alters VSM β adrenergic-mediated cAMP signaling and vasodilation, which may contribute to the dysregulation of vascular reactivity and the development of vascular complications for nicotine-containing product users.

Keyphrases

smooth muscle
smoking cessation
binding protein
risk factors
protein kinase