Bisphosphonate Use and Risk of Atypical Femoral Fractures: A Danish Case Cohort Study with Blinded Radiographic Review.
Douglas C BauerDennis M BlackRick DellBo FanChristopher D SmithMartin T ErnstAnne G JurikJens B FrøkjærMikael BoesenEric VittinghoffBo AbrahamsenPublished in: The Journal of clinical endocrinology and metabolism (2024)
The risk of AFF increases with duration of BP use but the beneficial effects of BP therapy in adults ≥50 dramatically exceed this increased risk. Nearly one-third of those with AFF have no BP exposure.