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Effect of niraparib on cardiac repolarization in patients with platinum-sensitive, recurrent epithelial ovarian, fallopian tube, and primary peritoneal cancer.

Kathleen M MooreJohn K ChanAngeles Alvarez SecordManish R PatelTimothy CallahanWei GuoZhi-Yi Zhang
Published in: Cancer chemotherapy and pharmacology (2019)
Niraparib administration at the recommended daily dose of 300 mg for EOC is not associated with clinically relevant alteration of ECGs, including QTc prolongation.
Keyphrases
  • papillary thyroid
  • squamous cell
  • left ventricular
  • drug induced
  • heart failure
  • lymph node metastasis
  • childhood cancer
  • squamous cell carcinoma
  • young adults