Effect of niraparib on cardiac repolarization in patients with platinum-sensitive, recurrent epithelial ovarian, fallopian tube, and primary peritoneal cancer.
Kathleen M MooreJohn K ChanAngeles Alvarez SecordManish R PatelTimothy CallahanWei GuoZhi-Yi ZhangPublished in: Cancer chemotherapy and pharmacology (2019)
Niraparib administration at the recommended daily dose of 300 mg for EOC is not associated with clinically relevant alteration of ECGs, including QTc prolongation.