Biomarkers of oxidative stress and its nexus with haemoglobin variants and adverse foeto-maternal outcome among women with preeclampsia in a Ghanaian population: A multi-centre prospective study.
Ganiwu AbdulWilliam Osei-WusuGordon Akuffo AsareSamira DaudStephen OpokuValentine Christian Kodzo Tsatsu TamakloeJoseph FrimpongBenedict SackeyWina Ivy Ofori BoaduVivian PaintsilMax Efui Annani-AkollorYaw Amo WiafeEnoch Odame AntoOtchere Addai-MensahPublished in: PloS one (2023)
Reduced levels of vitamin C are common among preeclamptics with at least one copy of the HbC variant. Haemoglobin variants in preeclampsia contribute to adverse foeto-maternal outcomes with Haemoglobin S variants being the most influencing factor for PPH, HELLP, preterm labour, NICU admission, and neonatal jaundice.
Keyphrases
- copy number
- pregnancy outcomes
- oxidative stress
- early onset
- birth weight
- emergency department
- preterm infants
- gestational age
- pregnant women
- dna damage
- low birth weight
- body mass index
- metabolic syndrome
- physical activity
- adverse drug
- preterm birth
- insulin resistance
- genome wide
- weight gain
- endoplasmic reticulum stress