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A bioinformatics investigation into the pharmacological mechanisms of javanica oil emulsion injection in non-small cell lung cancer based on network pharmacology methodologies.

Mengwei NiXinkui LiuZiqi MengShuyu LiuShanshan JiaYingying LiuWei ZhouJia-Rui WuJingyuan ZhangSiyu GuoJialin LiHaojia WangXiaomeng Zhang
Published in: BMC complementary medicine and therapies (2020)
In conclusion, this study predicted and verified that the mechanism of JOEI against NSCLC involves multiple targets and signaling pathways. Furthermore, this study provides candidate targets for the treatment of NSCLC, lays a good foundation for further experimental research and promotes the reasonable application of JOEI in clinical treatment.
Keyphrases
  • small cell lung cancer
  • signaling pathway
  • advanced non small cell lung cancer
  • tyrosine kinase
  • endoplasmic reticulum stress