Combinatorial effect of radium-223 and irreversible electroporation on prostate cancer bone metastasis in mice.
Raniv D RojoJoy Vanessa D PerezJossana A DamascoGuoyu YuSong-Chang LinFrancisco M HeraldeNora M NovoneElmer B SantosSue-Hwa LinMarites P MelanconPublished in: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group (2021)
IRE in combination with Ra-223, which enhanced the destruction of cancer cells that are adjacent to bone, resulted in reduction of tumor recurrence through improved clearance of proliferative cells in the tumor region.
Keyphrases
- prostate cancer
- induced apoptosis
- bone mineral density
- endoplasmic reticulum stress
- rheumatoid arthritis
- soft tissue
- cell cycle arrest
- bone loss
- bone regeneration
- type diabetes
- high fat diet induced
- oxidative stress
- cell death
- systemic sclerosis
- signaling pathway
- metabolic syndrome
- interstitial lung disease
- body composition
- skeletal muscle
- insulin resistance
- disease activity