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LncRNA LINC00974 activates TGF-β/Smad signaling to promote oral fibrogenesis.

Chih-Yuan FangCheng-Chia YuYi-Wen LiaoPei-Ling HsiehMing-Yi LuKuan-Chou LinChing-Zong WuLo-Lin Tsai
Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2018)
Altogether, these findings suggested that arecoline-increased myofibroblast transdifferentiation was via LINC00974-mediated activation of TGF-β signaling.
Keyphrases
  • transforming growth factor
  • long non coding rna
  • long noncoding rna
  • epithelial mesenchymal transition
  • cell proliferation
  • signaling pathway