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[Application of single-sperm sequencing in resolving the carrier status of preimplantation genetic testing for chromosomal structural rearrangements in Robertsonian translocations].

Bao-Qiong LiaoLi-Dan LaiRu-Tian LiuQi ZhangWen-Chang LianWu-Ming Xie
Published in: Zhonghua nan ke xue = National journal of andrology (2024)
For male carriers of Robertsonian translocation, single sperm sequencing can be used to screen SNP sites to construct haplotypes for distinguishing normal and Robertsonian translocation embryos, and to provide a basis for embryo selection by preimplantation chromosomal structural genetic testing.
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