Structural applications of the isotropic liquid-phase deuterium nuclear magnetic resonance.

Present review is focused on recent experimental and computational advances of the liquid-phase deuterium nuclear magnetic resonance (NMR). Nowadays, isotropic liquid-phase 2 H NMR became one of the most important instruments for the identification and certification of organic compounds of biological interest together with natural products and biosynthetic molecules. Of special interest are the 2 H NMR biochemical and microbiological applications. This review consists of three main parts. The first part deals with the practical applications of 2 H NMR to organic compounds of biological interest. The second part is connected with natural products and biosynthetic molecules, while the third part exemplifies and outlines 2 H NMR advances in biochemistry and microbiology.