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A Critical Appraisal and Recommendations for Cost-Effectiveness Studies of Poly(ADP-Ribose) Polymerase Inhibitors in Advanced Ovarian Cancer.

Wei GaoDominic MustonMatthew MonbergKimmie McLaurinRobert HettleElizabeth SzamretaElyse SwallowSu ZhangIden KalemajJames SignorovitchR Brett McQueen
Published in: PharmacoEconomics (2021)
In the existing CEAs for PARP inhibitors, there were uncertainties and challenges leading to variation in quality. We provided recommendations to improve consistency and quality of CEAs in this setting, which will help to better understand the value of PARP inhibitors, improve decision making, and reduce potential misallocation of resources.
Keyphrases
  • decision making
  • dna damage
  • dna repair
  • clinical practice
  • quality improvement
  • oxidative stress
  • structural basis