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Impact of Interferons and Biological Drug Inhibitors of IL-2 and IL-6 on Small-Molecule Drug Metabolism Through the Cytochrome P450 System.

C Michael WhiteDakota J SicignanoKimberly Smith
Published in: The Annals of pharmacotherapy (2021)
Interferon therapy or inflammatory suppression via IL-2 or IL-6 can alter steady-state concentrations of CYP-metabolized small-molecule drugs.
Keyphrases
  • small molecule
  • protein protein
  • oxidative stress
  • stem cells
  • emergency department
  • adverse drug
  • drug induced
  • bone marrow
  • mesenchymal stem cells
  • cell therapy
  • electronic health record