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Genetic predisposition to fetal and neonatal cancer.

A EscuderoB Ruz-CaracuelD BuenoM MartínezP RubioR M RegojoE AntolínM YbarraL MartínezJ J Pozo-KreilingerM D ElorzaA PellicerF OmeñacaAdela Escudero
Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2021)
Our results suggest that genetic factors have almost no higher impact in most neonatal tumors. However, since the heterogeneity of the tumors and the small sample size analyzed, we recommend complementary and centralized germline studies to discard the early onset as an additional criterion to take into account to improve the identification of cancer genetic predisposition syndromes in neonates.
Keyphrases
  • early onset
  • papillary thyroid
  • genome wide
  • late onset
  • copy number
  • lymph node metastasis
  • single cell
  • oxidative stress
  • young adults
  • childhood cancer
  • preterm infants
  • dna damage