Pd-Catalyzed Selective B(6)-H Phosphorization of nido -Carboranes via Cascade Deboronation/B-H Activation from closo -Carboranes.

Efficient Pd-catalyzed regioselective B(6)-H phosphorization of nido -carboranes via cascade deboronation/B-H activation of readily available C-substituted o -carboranes with various phosphines using 3-methylpyridine or isoquinoline as a directing group in combination with pyridine ligands has been developed, affording unprecedented B(6)-phosphinated nido -carborane derivatives with high selectivity in a simple one-pot process.