Login / Signup
TP63-TRIM29 axis regulates enhancer methylation and chromosomal instability in prostate cancer.
R Sultanov
A Mulyukina
O Zubkova
A Fedoseeva
A Bogomazova
K Klimina
A Larin
T Zatsepin
T Prikazchikova
M Lukina
M Bogomiakova
E Sharova
E Generozov
M Lagarkova
G Arapidi
Published in:
Epigenetics & chromatin (2024)
Our study demonstrates that TRIM29 and TP63 are important regulators in maintaining the identity of the basal epithelium under physiological conditions. Furthermore, we uncover the role of TRIM29 in PRAD development.
Keyphrases
</>
prostate cancer
transcription factor
radical prostatectomy
dna methylation
binding protein
copy number