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Do periodontal defects affect periodontal inflammation and destruction? Histological/microbiological changes and gene expression profiles of a pilot study in beagle dogs.

Yin-Zhe AnKyung-A KoChang-Sung KimReinhard GruberXinhong WangJung-Seok Lee
Published in: Journal of periodontology (2020)
Intrabony defect might exaggerate the plaque-induced inflammation in the aspect of inflammatory cell infiltration and the related gene expression, but both dental plaque and the pre-existing periodontal defect negligibly disrupt periodontal attachment and the underlying alveolar bone.
Keyphrases
  • gene expression
  • oxidative stress
  • dna methylation
  • coronary artery disease
  • diabetic rats
  • single cell
  • stem cells
  • high glucose
  • mesenchymal stem cells
  • bone marrow
  • oral health