Do periodontal defects affect periodontal inflammation and destruction? Histological/microbiological changes and gene expression profiles of a pilot study in beagle dogs.
Yin-Zhe AnKyung-A KoChang-Sung KimReinhard GruberXinhong WangJung-Seok LeePublished in: Journal of periodontology (2020)
Intrabony defect might exaggerate the plaque-induced inflammation in the aspect of inflammatory cell infiltration and the related gene expression, but both dental plaque and the pre-existing periodontal defect negligibly disrupt periodontal attachment and the underlying alveolar bone.