Clinical Application of Forced Oscillation Technique (FOT) in Early Detection of Airway Changes in Smokers.
Prem BhattaraiStephen MyersCollin ChiaHeinrich C WeberSally YoungAndrew D WilliamsSukhwinder Singh SohalPublished in: Journal of clinical medicine (2020)
The forced oscillation technique (FOT) is a non-invasive method to assess airway function by emitting oscillatory signals into the respiratory tract during tidal ventilation. This opinion piece discusses the current use, trialled modification and future directions in utilizing FOT as a novel diagnostic tool for early detection of small airway changes in smokers. The published evidence to date has shown that FOT parameters could be a sensitive diagnostic tool to detect early respiratory changes in smokers. Multiple frequencies and the frequency dependence of resistance and reactance can provide the most valuable and early information regarding smoking induced changes in airways. Considering its non-invasiveness, lower level of discomfort to patients than spirometry, feasibility, and cost effectiveness, it could be the first-choice diagnostic technique for detection of early respiratory changes in smokers. The finding of FOT could further be supported and correlated with inflammatory markers.
Keyphrases
- smoking cessation
- respiratory tract
- high frequency
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- prognostic factors
- peritoneal dialysis
- systematic review
- intensive care unit
- quantum dots
- chronic obstructive pulmonary disease
- air pollution
- patient reported outcomes
- fluorescent probe
- health information
- acute respiratory distress syndrome
- current status
- real time pcr
- extracorporeal membrane oxygenation