Transient Hypoxia Model Revealed Cerebrovascular Impairment in Anemia Using BOLD MRI and Near-Infrared Spectroscopy.
Julie ColoignerChau VuMatthew BorzageAdam M BushSoyoung ChoiXin MiaoYaqiong ChaiCristina GalarzaNatasha LeporeBenita TamraziThomas D CoatesJohn C WoodPublished in: Journal of magnetic resonance imaging : JMRI (2020)
Transient hypoxia revealed global and regional response differences between anemic and healthy subjects. SCI was associated with extensive heterogeneity of desaturation dynamics, consistent with extensive underlying microvascular remodeling.