Login / Signup

Associations of common variants in the SLC16A11, TCF7L2, and ABCA1 genes with pediatric-onset type 2 diabetes and related glycemic traits in families: A case-control and case-parent trio study.

América L Miranda-LoraMiguel CruzMario Molina-DíazJorge GutiérrezSamuel Flores-HuertaMiguel Klünder-Klünder
Published in: Pediatric diabetes (2017)
The results suggest that SLC16A1 /rs13342232 might be involved in the risk of pediatric-onset T2D in Mexican families. Moreover, TCF7L2/rs122555372 was associated with pancreatic reserve in patients with T2D and with fasting glucose and β-cell function in individuals without diabetes.
Keyphrases
  • type diabetes
  • glycemic control
  • blood glucose
  • case control
  • genome wide
  • insulin resistance
  • cardiovascular disease
  • dna methylation
  • gene expression
  • young adults
  • adipose tissue
  • skeletal muscle
  • blood pressure