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Oxidation of hemoproteins by Streptococcus pneumoniae collapses the cell cytoskeleton and disrupts mitochondrial respiration leading to the cytotoxicity of human lung cells.

Anna ScasnyBabek AlibayovFaidad KhanShambavi J RaoLandon MurinAna G Jop VidalPerriann SmithWei LiKristin EdwardsKurt WarnckeJorge E Vidal
Published in: Microbiology spectrum (2023)
plays an important role in the cytotoxicity caused by Spn, thus providing new targets for interventions.
Keyphrases
  • induced apoptosis
  • oxidative stress
  • cell cycle arrest
  • single cell
  • physical activity
  • endoplasmic reticulum stress
  • signaling pathway
  • cell death
  • cell proliferation
  • electron transfer