Causality of anthropometric markers associated with polycystic ovarian syndrome: Findings of a Mendelian randomization study.

Both and general- and central obesity yield total causal effects on PCOS. Findings also indicated potential direct causal effects of normal weight-central obesity and more complex causal mechanisms when both central- and general obesity are present. Results underscore the importance of addressing both central- and general obesity for optimizing PCOS care.