Bringing precision medicine to the management of pregnancy in women with glucokinase-MODY: a study of diagnostic accuracy and feasibility of non-invasive prenatal testing.

Alice E Hughes Jayne A L HoughtonBenjamin BunceAli Jason ChakeraGill SpyerMaggie H Shepherd Sarah E. Flanagan Andrew T Hattersley

Published in: Diabetologia (2023)

Non-invasive prenatal testing of fetal genotype in GCK-MODY pregnancies is highly accurate and is capable of providing a result before the last trimester for most patients. This means that non-invasive prenatal testing of fetal genotype is the optimal approach to management of GCK-MODY pregnancies.

Keyphrases

preterm birth
pregnant women
pregnancy outcomes
gestational age
end stage renal disease
newly diagnosed
ejection fraction
high resolution