Antiphospholipid antibodies in patients with myocardial infarction with and without obstructive coronary arteries.
Elisabet SvenungssonJonas SpaakKarin StrandbergHåkan N WallénStefan AgewallElin B BrolinOlov CollsteMaria DanielChristina EkenbäckMats FrickLoghman HenarehKarin MalmqvistKerstin ElvinPeder SörenssonShams Y-HassanClaes Hofman-BangPer TornvallPublished in: Journal of internal medicine (2021)
aPL IgG, but not IgA/M, are enriched particularly in patients with MICAD but also in patients with MINOCA, as compared to controls. Interestingly, signs of hypercoagulability-measured by increased levels of the APC-PCI complex-were present in aPL IgG-positive MICAD patients, indicating an association with functional disturbances of the coagulation system.
Keyphrases
- end stage renal disease
- coronary artery disease
- ejection fraction
- chronic kidney disease
- heart failure
- systemic lupus erythematosus
- coronary artery
- acute myocardial infarction
- peritoneal dialysis
- prognostic factors
- left ventricular
- percutaneous coronary intervention
- atrial fibrillation
- st elevation myocardial infarction
- coronary artery bypass