Long-term Variability in Glycemic Control Is Associated With White Matter Hyperintensities in APOE4 Genotype Carriers With Type 2 Diabetes.
Abigail LivnyRamit Ravona-SpringerAnthony D HeymannRachel PriessTammar KushnirGalia TsarfatyLeeron RabinovReut MoranHadass HoffmanItzik CooperLior GreenbaumJeremy SilvermanMary SanoSterling C JohnsonBarbara B BendlinMichal Schnaider BeeriPublished in: Diabetes care (2016)
The results suggest that the APOE4 genotype affects the relationship of long-term glycemic control with WMH load so that APOE4 carriers may be more vulnerable to the insults of poor control.