Solid carcinoma is a variant of microcystic adnexal carcinoma: A 14-case series.

Mar Llamas VelascoYosmar Carolina Pérez-GónzalezRamon Bosch-PríncepMaría-Teresa Fernández-FiguerasArno Rütten

Published in: Journal of cutaneous pathology (2018)

Solid carcinoma is a solid variant of MAC affecting the scalp more frequently than classic MAC, mostly in old males and showing variable-sized nests involving the entire dermis and composed by poroid, clear-cells, or a mixture of both. It is positive for p63 and CK5/6 and negative for BerEP4 and PHLDA-1. Staining features with CK19 and PHLDA1 differ from classic MAC.

Keyphrases

induced apoptosis
protein kinase
cell cycle arrest
cell proliferation
endoplasmic reticulum stress
pi k akt