CDK5R1, GSE1, HSPG2 and WDFY3 as indirect epigenetic-sensitive genes in atrial fibrillation.
Teresa InfanteMark E PepinAntonio RuoccoUgo TramaCiro MauroClaudio NapoliPublished in: European journal of clinical investigation (2023)
CDK5R1, GSE1, HSPG2 and WDFY3 resulted the best discriminatory genes both at methylation and gene expression level. Our results provide several candidate diagnostic biomarkers with the potential to advance precision medicine in AF.
Keyphrases
- gene expression
- dna methylation
- genome wide
- atrial fibrillation
- cell cycle
- bioinformatics analysis
- genome wide identification
- oral anticoagulants
- heart failure
- left atrial
- catheter ablation
- left atrial appendage
- direct oral anticoagulants
- cell proliferation
- percutaneous coronary intervention
- transcription factor
- risk assessment
- coronary artery disease
- acute coronary syndrome
- climate change
- mitral valve