A novel lncRNA-miRNA-mRNA triple network identifies lncRNA TWF1 as an important regulator of miRNA and gene expression in coronary artery disease.

Liu MiaoRui-Xing YinQing-Hui ZhangXi-Jiang HuFeng HuangWu-Xian ChenXiao-Li CaoJin-Zhen Wu

Published in: Nutrition & metabolism (2019)

This investigation on the regulatory networks of lncRNA-miRNA-mRNA in CAD suggests that a novel lncRNA, lncRNA TWF1 is a risk factor for CAD, and expands our understanding into the mechanisms involved in the pathogenesis of CAD.

Keyphrases

coronary artery disease
long non coding rna
gene expression
long noncoding rna
cardiovascular events
percutaneous coronary intervention
transcription factor
coronary artery bypass grafting
dna methylation
cardiovascular disease
genome wide
acute coronary syndrome
atrial fibrillation