Inverse association between apolipoprotein C-II and cardiovascular mortality: role of lipoprotein lipase activity modulation.
Günther SilbernagelYan Q ChenMartin RiefMarcus Edi KleberMichael M HoffmannTatjana StojakovicAndreas StangMark A SarzynskiClaude BouchardWinfried MärzYue-Wei QianHubert ScharnaglRobert J KonradPublished in: European heart journal (2023)
The present epidemiologic data suggest that increasing low circulating ApoC-II levels may reduce cardiovascular risk. This conclusion is supported by the observation that optimal ApoC-II concentrations are required for maximal GPIHBP1-LPL enzymatic activity.