Impact of opioid dose escalation on the development of substance use disorders, accidents, self-inflicted injuries, opioid overdoses and alcohol and non-opioid drug-related overdoses: a retrospective cohort study.

Corey J HayesErin E KrebsTeresa HudsonJoshua BrownChenghui LiBradley C Martin

Published in: Addiction (Abingdon, England) (2020)

Escalating the opioid dose for those with chronic, non-cancer pain is associated with increased risks of substance use disorder and opioid-related adverse outcomes.

Keyphrases

chronic pain
pain management
squamous cell carcinoma
emergency department
spinal cord
open label
neuropathic pain
alcohol consumption
squamous cell