Rewiring the altered tryptophan metabolism as a novel therapeutic strategy in inflammatory bowel diseases.
Chloé MichaudelCamille DanneAllison AgusAurélie MagniezAnne AucouturierMadeleine SpatzAntoine LefevreJulien KirchgesnerNathalie RolhionYazhou WangAonghus LavelleChloé GalbertGregory Da CostaMaxime PoirierAlexia LapièreJulien PlanchaisPetr NádvorníkPeter IllesCyriane OeuvrayLaura CreusotMarie-Laure MichelNicolas BenechAnne BourrierIsabelle Nion-LarmurierCecilia LandmanMathias L RichardPatrick EmondPhilippe SeksikLaurent BeaugerieRafael Rose ArguelloDavid MoulinSridhar ManiZdenek DvorákLuis G Bermúdez-HumaránPhilippe LangellaHarry SokolPublished in: Gut (2022)
T cells. This study paves the way for new therapeutic strategies aiming at pharmacologically correcting its alterations in IBD by manipulating the endogenous metabolic pathway with AADAT.
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