A novel <sup>18</sup>F-labeled agonist for PET imaging of stimulator of interferon gene expression in tumor-bearing mice.

Jianyang FangLixia FengLingxin MengXiaobo WangHuanhuan LiuLumei HuangDeliang ZhangJingchao LiRongqiang ZhuangZhide GuoXianzhong Zhang

Published in: European journal of nuclear medicine and molecular imaging (2022)

This proof-of-concept study demonstrated a STING-binding radioligand for PET imaging, which could be used as a potential companion diagnostic tool for related STING-agonist therapies.

Keyphrases

wild type
pet imaging
gene expression
positron emission tomography
dna methylation
dendritic cells
computed tomography
binding protein
type diabetes
adipose tissue
climate change
high fat diet induced
insulin resistance
drug induced