ChemR23 signaling ameliorates brain injury via inhibiting NLRP3 inflammasome-mediated neuronal pyroptosis in ischemic stroke.
Lan LiuJiawei ZhangKaili LuYaxuan ZhangXiaofeng XuJiangshan DengXiaojie ZhangHaibing ZhangYuwu ZhaoXiuzhe Wang
Published in: Journal of translational medicine (2024)
Our data indicated that ChemR23 modulates NLRP3 inflammasome-mediated neuronal pyroptosis in ischemic stroke. Activation of ChemR23 may serve as a promising potential target for neuroprotection in cerebral ischemia.