High incidences of chromosomal aberrations and Y chromosome micro-deletions as prominent causes for recurrent pregnancy losses in highly ethnic and consanguineous population.
Arshad A PandithUsma ManzoorIna Aminnull Dil-AfrozeAbida AhmadMasarat RashidMahrukh H ZargarShayesta RahFayaz A DarIqbal QasimDheera SanadhyaPublished in: Archives of gynecology and obstetrics (2021)
We conclude 15.2% couples affected either by chromosomal or Y chromosome deletions contribute hugely in the diagnosis and management of repeated pregnancy losses. It is recommended that couples that belong to consanguineous and multigenerational group of RM should be considered for cytogenetic and molecular testing after two abortions for successful pregnancy outcomes and management of RM.