Functional MRI reveals effects of high intraocular pressure on central nervous system in high-tension glaucoma patients.
Yi WangWeizhao LuTingqin YanJian ZhouYuanzhong XieJiumin YuanGuangling LiuYufang TengWenhui HanDi ChenJianfeng QiuPublished in: Acta ophthalmologica (2019)
Resting-state fMRI ReHo analyses associated elevated IOP with abnormal regional activity in several brain regions related to higher visual function and visual memory consolidation. High-tension glaucoma patients also showed diminished integration of visual information and cerebellar function. These results may provide imaging support for pathophysiological research of HTG and may reveal new targets for the accurate treatment of HTG.
Keyphrases
- resting state
- functional connectivity
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- peritoneal dialysis
- high resolution
- magnetic resonance imaging
- prognostic factors
- healthcare
- blood brain barrier
- optical coherence tomography
- mass spectrometry
- brain injury
- cerebrospinal fluid
- smoking cessation
- diffusion weighted imaging