Functional connectivity between the habenula and default mode network and its association with the antidepressant effect of ketamine.

Mingqia WangXiaoyu ChenYiru HuYangling ZhouChengyu WangWei ZhengWeijian LiuXiaofeng LanYu-Ping Ning Bin Zhang

Published in: Depression and anxiety (2021)

These pilot findings may suggest a potential neural mechanism by which ketamine exerts its robust antidepressant efficacy via downregulation of aberrant habenular FC with parts of the default mode network.

Keyphrases

functional connectivity
resting state
major depressive disorder
pain management
study protocol
clinical trial
human health
climate change