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Measurement of 8-hydroxy-2'-deoxyguanosine in serum and cerebrospinal fluid of horses with neuroaxonal degeneration and other causes of proprioceptive ataxia.

Megan PalmisanoJeaneen KulpSusan BenderDarko StefanovskiMary RobinsonAmy Johnson
Published in: Journal of veterinary internal medicine (2024)
Eight-OHdG did not aid in antemortem diagnosis of NAD/DM in this cohort of horses. At the time of diagnosis horses with NAD/DM do not have ongoing oxidative stress.
Keyphrases
  • oxidative stress
  • cerebrospinal fluid
  • dna damage
  • early onset
  • type diabetes
  • glycemic control
  • adipose tissue
  • signaling pathway