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Dynamics of circulating tumor DNA during postoperative radiotherapy in patients with residual triple-negative breast cancer following neoadjuvant chemotherapy: a prospective observational study.

Haeyoung KimYeon Jeong KimDonghyun ParkWoong-Yang ParkDoo Ho ChoiWon ParkWon Kyung ChoNalee Kim
Published in: Breast cancer research and treatment (2021)
Among patients with post-NAC residual TNBC, more than a quarter exhibited a detectable amount of ctDNA after curative surgery. The ctDNA VAF changed variably during the course of PORT. Therefore, ctDNA kinetics can serve as a biomarker for optimizing adjuvant treatment.
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